Epigenomics The epigenome isn't just some biological afterthought The Epigenome: What it can tell us and why we should care to look at it thoughtfully.
DNA Is the genetic material protein or DNA? A blender decided. Deoxyribonucleic acid (DNA) is the genetic material, but early on, most of science thought the genetic material was protein. That changed in 1952.
Weekly Reading List Weekly Reading List: Dec 23, 2024 CRISPR genome-editing grows up: advanced therapies head for the clinicGene-editing technologies for cancer and blood disorders are maturing a little more than a year after the first CRISPR drug was approved.NatureHeidi Ledford Study Failure Spotlights Challenges for ctDNA Strategies in Breast Cancer Drug Trials Researchers stopped a Phase III
Omic.ly Premium 55 December 23, 2024 Hey There! Thanks for spending part of your holiday with Omic.ly! This Week's Headlines 1) HOT TAKE: The week of Sequence-mas 2) Our skin has it's own distinct immune system 3) The epigenome isn't just some biological afterthought 4) Is
Microbiomics Expert panel on clinical microbiome use: "More evidence needed" An international panel says clinical microbiomes aren't ready for primetime...yet
Epigenetics There are lots of tools for probing the epigenome If epigenetics is the study of modifications that aren't coded in the DNA, how can we use DNA sequencing to learn anything about the epigenome?
High-Throughput Sequencing Automated sanger sequencing's fluorescent beginnings We ‘completed’ the human genome in 2003, thanks mostly to commercial industrial engineering.
Omic.ly Weekly 54 December 16, 2024 Hey There! Thanks for spending part of your week with Omic.ly! This Week's Headlines 1) Expert panel on clinical microbiome use: "More evidence needed" 2) There are lots of tools for probing the epigenome 3) Automated sanger sequencing's fluorescent beginnings
Paid-members only Regulations HOT TAKE: With lawsuits percolating in the background, CAP, Congress and others start working on VALID 2.0
Artificial Intelligence Foundation models are all the rage today - Now there's one for genomes! EvoAI: a genome foundation model for building prokaryotes
Epigenetics Epigenetics! You've heard of it, but what do you know about it? There are lots of ‘omes: There's the genome, transcriptome, proteome, and metabolome - but the one above them all is the epigenome.
Cloning Dolly the sheep stole our hearts in 1997 6LL3, better known as Dolly the sheep, showed that mammalian cloning was possible in 1997.
Omic.ly Weekly 53 December 9, 2024 Hey There! Thanks for spending part of your week with Omic.ly! This Week's Headlines 1) Foundation models are all the rage today - Now there's one for genomes! 2) Epigenetics! You've heard of it, but what do you know about
Paid-members only FDA Just when you thought you might be safe, FDA sticks its nose into MRD testing (again)
Artificial Intelligence RhoFold+: A large language model for RNA structure prediction Can LLMs predict RNA structures?
RNA Direct RNA sequencing might tell us about more than just the bases Post-transcriptional modifications: Why sequencing RNA directly is the future of transcriptomics
Historical Paper Review Oswald Avery, Colin Macleod and Maclyn McCarty showed that DNA was the genetic material in 1944 One of the most important papers in the history of genetics was basically ignored when it was published in 1944.
