Paid-members only Regulations HOT TAKE: With lawsuits percolating in the background, CAP, Congress and others start working on VALID 2.0
Artificial Intelligence Foundation models are all the rage today - Now there's one for genomes! EvoAI: a genome foundation model for building prokaryotes
Epigenetics Epigenetics! You've heard of it, but what do you know about it? There are lots of ‘omes: There's the genome, transcriptome, proteome, and metabolome - but the one above them all is the epigenome.
Cloning Dolly the sheep stole our hearts in 1997 6LL3, better known as Dolly the sheep, showed that mammalian cloning was possible in 1997.
Paid-members only FDA Just when you thought you might be safe, FDA sticks its nose into MRD testing (again)
Artificial Intelligence RhoFold+: A large language model for RNA structure prediction Can LLMs predict RNA structures?
RNA Direct RNA sequencing might tell us about more than just the bases Post-transcriptional modifications: Why sequencing RNA directly is the future of transcriptomics
Historical Paper Review Oswald Avery, Colin Macleod and Maclyn McCarty showed that DNA was the genetic material in 1944 One of the most important papers in the history of genetics was basically ignored when it was published in 1944.
Paid-members only How might the election change how FDA approaches enforcement of their new LDT rule?
Diagnostics Metagenomics hits the clinic to diagnose CNS infections Whole genome metagenomics is better than the standard of care in detecting the causal bugs of CNS infections
Transcriptomics Transcriptomics is better with long-reads Spoiler Alert: The holy grail of transcriptomics is long-reads.
Molecular Biology Molecular Biology is the offspring of biochemistry and genetics The field of molecular biology was born in 1941 through the marriage of genetics and biochemistry.
Nanopores Nanopores are getting on the rapid NICU/PICU sequencing bandwagon Nanopores take on rapid neonatal sequencing
Transcriptomics New tech always has risks and limitations, single-cell and spatial transcriptomics are no exception Single-Cell and Spatial Transcriptomics: Risks, Limitations, and Questions to Ask
Historical Paper Review A wormy discovery becomes a knockout laboratory technique One of the best ways to figure out what a gene does is to get rid of it and see what happens.
Artificial Intelligence AI takes on virus evolution AI to the rescue: using protein structural similarities to track virus evolution.
Transcriptomics Applications of single-cell and spatial transcriptomics Single cell and spatial transcriptomics: Let's explore some applications!
Historical Paper Review Fred Sanger didn't get his first Nobel for DNA sequencing Fred Sanger received a Nobel Prize for his work with Insulin. As the father of DNA sequencing, this surely was for insulin's nucleic acid sequence? It wasn't.
